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oral candidiasis : ウィキペディア英語版 | oral candidiasis
Oral candidiasis (also known as oral candidosis, oral thrush, oropharyngeal candidiasis, moniliasis, candidal stomatitis, muguet) is candidiasis that occurs in the mouth. That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth. ''Candida albicans'' is the most commonly implicated organism in this condition. ''C. albicans'' is carried in the mouths of about 50% of the world's population as a normal component of the oral microbiota. This candidal carriage state is not considered a disease, but when ''Candida'' species become pathogenic and invade host tissues, oral candidiasis can occur. This change usually constitutes an opportunistic infection of normally harmless micro-organisms because of local (i.e., mucosal), or systemic factors altering host immunity. ==Classification==
Being a type of candidiasis, oral candidiasis is a mycosis. Traditionally, oral candidiasis is classified using the Lehner system, originally described in the 1960s, into acute and chronic forms (see table). Some of the subtypes almost always occur as acute (e.g., acute pseudomembranous candidiasis), and others chronic. However, these typical presentations do not always hold true, which created problems with this system. A more recently proposed classification of oral candidiasis distinguishes ''primary oral candidiasis'', where the condition is confined to the mouth and perioral tissues, and ''secondary oral candidiasis'', where there is involvement of other parts of the body in addition to the mouth. The global human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic has been an important factor in the move away from the traditional classification since it has led to the formation of a new group of patients who present with atypical forms of oral candidiasis.〔
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